Stress, Alcohol, and Drugs: Effects on the Longevity of Caenorhabditis Elegans

by Emily Nielsen and Sarah Larson
Faculty advisor: Dr. James Hampton

The nematode Caenorhabditis elegans (C. elegans) has served as a model organism for the study of development, aging, and various other biological processes for over thirty years. Our research has examined the changes in lifespan of adult and dauer worms due to various compounds either inducing or alleviating oxidative stress. We have also examined the effects on adult mutants with cancer-like phenotypes in response to varying concentrations of curcumin, resveratrol, and taxol. In addition to presenting our findings, we will also discuss the nature and advantages of using C. elegans as a model organism.